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課程名稱 |
人腦映像方法
HUMAN BRAIN MAPPING METHODS |
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開課學期 |
98-2 |
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授課對象 |
學程 神經生物與認知科學學程 |
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授課教師 |
林發暄 |
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課號 |
Biomed7086 |
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課程識別碼 |
548 M1300 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三5,6,7(12:20~15:10) |
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上課地點 |
展書樓506 |
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備註 |
本課程中文授課,使用英文教科書。
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/982mhbm |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
Course Schedule
1 Introduction
2 Functional neural systems
2.1 Cellular electrophysiology
2.2 System neuroanatomy
3 Neurovascular coupling
4 Electrophysiological measurements (Magnetoencephalography)
4.1 Physiological origin
4.2 Forward problem
4.3 Inverse problem
5 Hemodynamic measurements (functional MRI)
5.1 Physiological origin
5.2 Contrast mechanisms (BOLD, flow/volume)
5.3 Experiment design
5.4 Pre-processing
5.5 Statistical analysis
6 Other measurements
6.1 Structure
6.2 Metabolism (MR spectroscopy)
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課程目標 |
This course focus on the introduction of modern non-invasive human neuroimaging facilities, including but not limited to, structural magnetic resonance imaging (MRI), functional magnetric resonance imaging (fMRI), MR spectroscopic imaging, and magnetocephalography (MEG). We will also include a very brief introduction to the cellular and system level neuroscience before presenting individual imaging methods. We wish to bring you a general concept of neuroimaging methods as well as their features, advantages, and limitations. |
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課程要求 |
*preferred backgounds* MRI physics, electromagnetics, system neuroscience, signal processing, statistics, linear algebra |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
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參考書目 |
Brain Mapping: The Methods (ISBN: 0126925402)
Arthur W. Toga, John C. Mazziotta
Academic Press; 1st edition (January 15, 1996)
Principles of Neural Science (ISBN: 0838577016)
Eric R. Kandel, James H. Schwartz, Thomas M. Jessell
McGraw-Hill Medical; 4 edition (January 5, 2000)
An Introduction to Functional Magnetic Resonance Imaging: Principles and
Techniques (ISBN: 0521002745)
R. B. Buxton
Cambridge University Press; Har/Cdr edition (December 15, 2001)
Functional Magnetic Resonance Imaging (ISBN: 0878932887)
Scott A. Huettel, Allen W. Song, Gregory McCarthy
Sinauer Associates; Har/Cdr edition (April 1, 2004)
The Human Brain: An Introduction to Its Functional Anatomy (ISBN: 0323013201)
John Nolte
Mosby; 5 edition (January 15, 2002) |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
course participation |
30% |
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2. |
quizes |
30% |
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3. |
final report |
40% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/24 |
introduction; history; time and space (舊:1,2,3 /新:2,4) |
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第2週 |
3/03 |
cellular electrophysiology (舊:1,2,3 /新:2,4) |
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第3週 |
3/10 |
system neuroanatomy (Dr. Tzu-Chen Yeh, VGH-Taipei) (舊:1,2,3 /新:2,4) |
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第4週 |
3/17 |
magnetic resonance imaging and echo-planar imaging (舊:1,2,3 /新:2,4) |
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第5週 |
3/24 |
brain structure: a diffusion MRI perspective (Dr. Wen-Yi Isaac Tseng, NTUH) (舊:1,2,3 /新:2,4) |
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第6週 |
3/31 |
hemodynamic measurements: BOLD fMRI (舊:1,2,3 /新:2,4) |
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第7週 |
4/07 |
sping break (no class) |
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第8週 |
4/14 |
hemodynamic measurements: analysis and application (Dr. Wen-Jui Kuo, National Yang Ming Univ.)(舊:1,2,3 /新:2,4) |
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第9週 |
4/21 |
hemodynamic measurements: perfusion (Dr. Wen-Chau Wu, NTU) (舊:1,2,3 /新:2,4) |
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第10週 |
4/28 |
metabolic measurements: MR spectroscopy and spectroscopic imaging (Dr. Shang-Yueh Tsai, Chang-Gung University) (舊:1,2,3 /新:2,4) |
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第11週 |
5/05 |
no class |
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第12週 |
5/12 |
final report discussion, electrophysiological measurements (MEG) (舊:1,2,3 /新:2,4) |
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第13週 |
5/19 |
Transcranial magnetic stimulation (TMS) (Dr. Chi-Hung Juan, National Central Univ.) (舊:1,2,3 /新:2,4) |
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第14週 |
5/26 |
electrophysiological measurements (MEG) (Dr. Yung-Yang Lin, National Yang Ming Univ.)(舊:1,2,3 /新:2,4) |
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第15週 |
6/02 |
no class |
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第16週 |
6/09 |
no class |
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第17週 |
6/16 |
final report |
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第18週 |
last |
課程期末問卷 |
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